![AffiAB® Anti-Hu CD108 FITC [MEM-150]](/web/image/product.product/82686/image_1024/%5BAFG-EXB-1187%5D%20AffiAB%C2%AE%20Anti-Hu%20CD108%20FITC%20%5BMEM-150%5D?unique=d31c23b)
Overview
CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors – plexin C1 and beta1 integrins.
Specificity:
The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes.
Antigen
CD108
Clone
MEM-150
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgM
Immunogen
HPB-ALL human T cell line
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
FITC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide