![AffiAB® Anti-Hu CD9 FITC [MEM-61]](/web/image/product.product/82654/image_1024/%5BAFG-EXB-1155%5D%20AffiAB%C2%AE%20Anti-Hu%20CD9%20FITC%20%5BMEM-61%5D?unique=d31c23b)
Overview
CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.
Specificity:
The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
Antigen
CD9
Clone
MEM-61
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Pre-B cell line NALM-6.
Application
FC (QC tested)
Regulatory status
RUO
Concentration
N/A
Format
FITC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide