![AffiAB® Anti-Cytokeratin 18 FITC [DC-10]](/web/image/product.product/82622/image_1024/%5BAFG-EXB-1123%5D%20AffiAB%C2%AE%20Anti-Cytokeratin%2018%20FITC%20%5BDC-10%5D?unique=0daa593)
Overview
Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 18 belongs to type I family (acidic cytokeratins) .
Specificity:
The mouse monoclonal antibody DC-10 reacts with cytokeratin 18 (45 kDa) . Cytokeratins are members of intermediate filaments subfamily of intracellular proteins, represented in epithelial tissues.
Antigen
Cytokeratin 18
Clone
DC-10
Species Reactivity
Human
Negative Species
Dog, Mouse, Rat, Pig, Hamster, Sheep, Cow
Isotype
Mouse IgG1
Immunogen
Human breast carcinoma cell line PMC-42.
Application
FC (QC tested)
Regulatory status
RUO
Concentration
0.1 mg/ml
Format
FITC
Storage / Stability
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide