![AffiAB® Anti-Ms Ly6G Biotin [RB6-8C5]](/web/image/product.product/82597/image_1024/%5BAFG-EXB-1098%5D%20AffiAB%C2%AE%20Anti-Ms%20Ly6G%20Biotin%20%5BRB6-8C5%5D?unique=0daa593)
Overview
Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses.
Specificity:
The rat monoclonal antibody RB6-8C5 detects Ly6G component of Gr-1 antigen, a commonly used surface marker of neutrophils.
Antigen
Ly6G
Clone
RB6-8C5
Species Reactivity
Mouse
Negative Species
N/A
Isotype
Rat IgG2b
Immunogen
Murine granulocytes
Application
WB, IHC (P), FC (QC tested), IP, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Biotin
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide