![AffiAB® Anti-Ms NK1.1 Purified Low Endotoxin [PK136]](/web/image/product.product/79762/image_1024/%5BAFG-EXB-0792%5D%20AffiAB%C2%AE%20Anti-Ms%20NK1.1%20Purified%20Low%20Endotoxin%20%5BPK136%5D?unique=06fe5f0)
Overview
NK1.1 / CD161bc (also known as NKRP1, Ly55c, or Ly59) is a cell surface antigen expressed on NK cells and NK-T cells of certain mouse strains, which is being used for identification or antibody-mediated depletion of these cells in the respective strains. This antigen participates in NK cell activation, including production of interferon gamma, and release of cytotoxic granules.
Specificity:
The mouse monoclonal antibody PK136 recognizes an extracellular epitope of NK1.1 antigen (NK cell marker) expressed by some mouse strains (e.g. C57BL/6, NZB, CE, C58, Ma/My), whereas other strains (e.g. BALB/c, AKR, CBA, C3H) do not express this antigen. This antibody detects a conformational epitope on Nkrp1c and Nkrp1b gene products.
Antigen
NK1.1
Clone
PK136
Species Reactivity
Mouse
Negative Species
N/A
Isotype
Mouse IgG2a kappa
Immunogen
NK1-positive murine splenic and bone marrow cells
Application
FC (QC tested), IP, IHC (F), FUNC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified Low Endotoxin
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4