![AffiAB® Anti-Hu CD82 Purified Low Endotoxin [C33]](/web/image/product.product/79717/image_1024/%5BAFG-EXB-0747%5D%20AffiAB%C2%AE%20Anti-Hu%20CD82%20Purified%20Low%20Endotoxin%20%5BC33%5D?unique=d31c23b)
Overview
CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
Specificity:
The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Antigen
CD82
Clone
C33
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
C91/PL (human HTLV-1+ T cell line)
Application
FC (QC tested), IP, WB, IHC (P), ICC, FUNC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified Low Endotoxin
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4