![AffiAB® Anti-Hu CD81 Purified Low Endotoxin [M38]](/web/image/product.product/79716/image_1024/%5BAFG-EXB-0746%5D%20AffiAB%C2%AE%20Anti-Hu%20CD81%20Purified%20Low%20Endotoxin%20%5BM38%5D?unique=d31c23b)
Overview
CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.
Specificity:
The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
Antigen
CD81
Clone
M38
Species Reactivity
Rabbit, Cat, Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
MOLT-4 (human T-ALL cell line)
Application
FC (QC tested), IP, WB, IHC (P), ICC, FUNC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified Low Endotoxin
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4