![AffiAB® Anti-Hu CD85g Purified Low Endotoxin [17G10.2]](/web/image/product.product/79686/image_1024/%5BAFG-EXB-0716%5D%20AffiAB%C2%AE%20Anti-Hu%20CD85g%20Purified%20Low%20Endotoxin%20%5B17G10.2%5D?unique=d31c23b)
Overview
CD85g / ILT7 (immunoglobulin-like transcript 7) is a cell surface protein that is expressed on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response, such as the TLR-induced interferon production. It associates with gamma subunit of the high-affinity IgE receptor to form a receptor complex which transduces the signal through ITAM-associated downstream molecules. Expression of CD85g is downregulated by interleukin 3.
Specificity:
The mouse monoclonal antibody 17G10.2 recognizes an extracellular epitope of CD85g / ILT7, a member of leukocyte immunoglobulin-like receptor family expressed on plasmacytoid dendritic cells, but not on myeloid dendritic cells and other peripheral blood leukocytes.
Antigen
CD85g
Clone
17G10.2
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
N/A
Application
FC (QC tested), FUNC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified Low Endotoxin
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4