![AffiAB® Anti-Hu CD303 Purified [15E3]](/web/image/product.product/79678/image_1024/%5BAFG-EXB-0708%5D%20AffiAB%C2%AE%20Anti-Hu%20CD303%20Purified%20%5B15E3%5D?unique=d31c23b)
Overview
CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.
Specificity:
The mouse monoclonal antibody 15E3 recognizes an extracellular epitope of human CD303, a transmembrane glycoprotein expressed on plasmacytoid dendritic cells.
Antigen
CD303
Clone
15E3
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
CD303 ectodomain fused with human IgG Fc domain
Application
ICC, ELISA, FC, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide