Overview
GAPDH (glyceraldehyde-3-phosphate dehydrogenase) is an intracellular homotetramerizing enzyme, which catalyzes oxidation of glyceraldehyde-3-phosphate into 1, 3-bisphosphoglycerate during glycolysis, and has also functions in DNA replication, gene expression, and microtubule bundling. As it binds to many proteins, its functions are very broad. GAPDH plays also roles in cancer progression, apoptosis, Huntington disease and Alzheimer´s disease.
Specificity:
The mouse monoclonal antibody FF26A recognizes human GAPDH (glyceraldehyne-3-phosphate dehydrogenase), a ubiquitously expressed 37 kDa enzyme involved in glycolysis and other processes.
Antigen
GAPDH
Clone
FF26A
Species Reactivity
Human
Negative Species
Mouse, Pig
Isotype
Mouse IgG1 kappa
Immunogen
human CD4-positive lymphocytes
Application
WB, IP, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide