![AffiAB® Anti-Hu CD245 Purified [DY12]](/web/image/product.product/79676/image_1024/%5BAFG-EXB-0706%5D%20AffiAB%C2%AE%20Anti-Hu%20CD245%20Purified%20%5BDY12%5D?unique=d31c23b)
Overview
CD245 is a 220-250 kDa transmembrane protein of unknown structure. It is expressed at lower level on resting blood lymphocytes, granulocytes, platelets, and thymocytes, and at high level on monocytes and on IL-2-dependent T cell lines. It is also expressed on Ewing sarcoma and osteosarcoma cell lines. CD245 seems to act as a costimulation molecule of T and NK cells.
Specificity:
The mouse monoclonal antibody DY12 recognizes an extracellular epitope of CD245, a transmembrane protein expressed mainly by peripheral blood lymphocytes, NK cells, monocytes, granulocytes and platelets.
Antigen
CD245
Clone
DY12
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
human NK-type YT2C2 cells
Application
WB, FC (QC tested), IHC, IP
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide