Overview
CD316 is an approximately 63 kDa transmembrane glycoprotein, which forms stable complexes with CD9, as well as with CD81. It seems that CD316 participates in regulation of cell polarity and motility, in cell proliferation, oocyte fertilization and tumor cell metastasis. It is expressed mainly by lymphocytes, NK cells and in a broad range of tissues, and associates with actin cytoskeleton.
Specificity:
The mouse monoclonal antibody 8A12 recognizes an extracellular epitope of CD316, a type I transmembrane glycoprotein, expressed mainly by lymphocytes, NK cells and in a broad range of tissues.
Antigen
CD316
Clone
8A12
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
human leukocytes
Application
WB, FC (QC tested), IP, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide