![AffiAB® Anti-Hu CD315 Purified [1F11]](/web/image/product.product/79674/image_1024/%5BAFG-EXB-0704%5D%20AffiAB%C2%AE%20Anti-Hu%20CD315%20Purified%20%5B1F11%5D?unique=d31c23b)
Overview
CD315, also known as prostaglandin F2 receptor negative regulator, is an approximately 135 kDa transmembrane glycoprotein, which associates with actin cytoskeleton, and with CD9 and CD81, but not with other tetraspanins. It seems to be involved in regulation of cell polarity and motility. CD315 is expressed mainly by keratinocytes, activated monocytes, and a subset of B cells, but it can be also used for distinguishing between strongly positive colon cancer and fibrosarcoma cells, and their negative normal cell counterparts.
Specificity:
The mouse monoclonal antibody 1F11 recognizes an extracellular epitope of CD315, a type I transmembrane glycoprotein expressed on keratinocytes, activated monocytes, and a subset of B cells.
Antigen
CD315
Clone
1F11
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
HeLa cells
Application
WB, FC (QC tested), IP, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide