![AffiAB® Anti-Hu CD156c Purified [11G2]](/web/image/product.product/79673/image_1024/%5BAFG-EXB-0703%5D%20AffiAB%C2%AE%20Anti-Hu%20CD156c%20Purified%20%5B11G2%5D?unique=d31c23b)
Overview
CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.
Specificity:
The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.
Antigen
CD156c
Clone
11G2
Species Reactivity
Human
Negative Species
Mouse
Isotype
Mouse IgG1 kappa
Immunogen
Jurkat cells
Application
WB, IHC (P), FC (QC tested), IP, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide