![AffiAB® Anti-Hu LOX1 Purified [15C4]](/web/image/product.product/79666/image_1024/%5BAFG-EXB-0696%5D%20AffiAB%C2%AE%20Anti-Hu%20LOX1%20Purified%20%5B15C4%5D?unique=06fe5f0)
Overview
LOX1, a 31 kDa type II transmembrane protein, is a C-type lectin, functioning as a scavenger receptor for e.g. oxidized low density lipoprotein, apoptotic heat shock proteins, or CRP. It is expressed by macrophages, fibroblasts, platelets, endothelial cells, and smooth muscle cells, and its defects can lead to atherosclerosis. Its expression is enhanced under inflammatory conditions. Multiple splicing variants have been identified.
Specificity:
The mouse monoclonal antibody 15C4 recognizes an extracellular epitope of LOX1, a C-type lectin transmembrane protein.
Antigen
LOX1
Clone
15C4
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a kappa
Immunogen
fusion protein of human LOX1 ectodomain and of human IgG Fc
Application
ICC, FC (QC tested), IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide