![AffiAB® Anti-Hu NKp80 Purified [5D12]](/web/image/product.product/79654/image_1024/%5BAFG-EXB-0684%5D%20AffiAB%C2%AE%20Anti-Hu%20NKp80%20Purified%20%5B5D12%5D?unique=06fe5f0)
Overview
NKp80, also known as CLEC5C or KLRF1, is a type II transmembrane glycoprotein of the C lectin family, which is expressed in 80 kDa homodimers on NK cells, and subsets of CD8+ alpha/beta T cells, and gamma/delta T cells. It belongs to the activating coreceptors, which induce cytotoxicity, and production of pro-inflammatory cytokines. Its ligand AICL is expressed on myeloid cells.
Specificity:
The mouse monoclonal antibody 5D12 recognizes an extracellular epitope of human NKp80 (CLEC5C), a C-type lectin family member, expressed on NK cells and subsets of T cells.
Antigen
NKp80
Clone
5D12
Species Reactivity
Human, Monkey
Negative Species
Mouse, Rat
Isotype
Mouse IgG1 kappa
Immunogen
recombinant human NKp80 extracellular domain
Application
FC (QC tested), IP
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide