![AffiAB® Anti-Hu CD49e Purified [SAM1]](/web/image/product.product/79652/image_1024/%5BAFG-EXB-0682%5D%20AffiAB%C2%AE%20Anti-Hu%20CD49e%20Purified%20%5BSAM1%5D?unique=06fe5f0)
Overview
CD49e (VLA5 alpha) is a type I transmembrane glycoprotein of the integrin alpha subclass (intergrin 5 alpha), expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells. It binds to RGD sequence in fibronectin and to neural adhesion molecule L1. CD49e interactions are important for maintaining the integrity of the endothelial monolayer, as well as it is involved in monocyte migration, T cell costimulation, regulation of cell survival, and other.
Specificity:
The mouse monoclonal antibody SAM1 recognizes an extracellular epitope of CD49e (integrin 5 alpha), a transmembrane glycoprotein expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells.
Antigen
CD49e
Clone
SAM1
Species Reactivity
Non-human primates, Human
Negative Species
N/A
Isotype
Mouse IgG2b
Immunogen
U937 cells
Application
FC (QC tested), IP, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide