![AffiAB® Anti-Hu CD319 Purified [162]](/web/image/product.product/79647/image_1024/%5BAFG-EXB-0677%5D%20AffiAB%C2%AE%20Anti-Hu%20CD319%20Purified%20%5B162%5D?unique=d31c23b)
Overview
CD319 is a homophilic type I transmembrane protein with two intracellular immunoreceptor tyrosine-based switch motives (ITSMs) . It is expressed by cytotoxic T cells, activated B cells, NK cells, and mature dendritic cells. CD319 triggers NK cell-mediated cytotoxicity. Ligation of CD319 can induce proliferation, cell adhesion, cytokine secretion, and cytotoxicity of T cells and NK cells.
Specificity:
The mouse monoclonal antibody 162 recognizes an extracellular epitope of human CD319, a transmembrane glycoprotein expressed by cytotoxic T cells, activated B cells, NK cells, and mature dendritic cells.
Antigen
CD319
Clone
162
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2b
Immunogen
Recombinant extracellular domain of human CD319 (204 aa) fused with Fc part of human IgG1
Application
IHC (P), FC (QC tested), IP
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide