![AffiAB® Anti-Hu CLEC2 Purified [AYP1]](/web/image/product.product/79633/image_1024/%5BAFG-EXB-0663%5D%20AffiAB%C2%AE%20Anti-Hu%20CLEC2%20Purified%20%5BAYP1%5D?unique=06fe5f0)
Overview
CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets. Platelet-aggregating snake venom protein rhodocytin also binds to CLEC2.
Specificity:
The mouse monoclonal antibody AYP1 recognizes an epitope within the extracellular part of CLEC2, a transmembrane glycoprotein expressed on activated plateles and on platelet microparticles.
Antigen
CLEC2
Clone
AYP1
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
A recombinant extracellular domain of human CLEC2 (amino acids 68-229)
Application
ICC, FC (QC tested), IP
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide