![AffiAB® Anti-p63 Purified [PANp63-6.1]](/web/image/product.product/79629/image_1024/%5BAFG-EXB-0659%5D%20AffiAB%C2%AE%20Anti-p63%20Purified%20%5BPANp63-6.1%5D?unique=06fe5f0)
Overview
The p53 family of proteins includes three members, p53, p63, and p73. The protein p63 is encoded by TP63 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp63) or absence (deltaNp63) of an N-terminal transactivation domain. Immunohistochemistry of p63 has a clinical relevance for certain tumor types, but investigations have been hampered by a lack of well characterized antibodies that are specific for p63 and do not cross-react with the related p53 and p73 proteins.
Specificity:
The mouse monoclonal antibody PANp63-6.1 recognizes both TAp63, and deltaNp63 form of p63. The target epitope PSHLIR is located within amino acids 261-266 of TAp63, and 167-172 of deltaNp63.
Antigen
p63
Clone
PANp63-6.1
Species Reactivity
Mouse, Rat, Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Recombinant full length human p63
Application
WB, IHC (P), ICC, IP
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide