![AffiAB® Anti-Hu CD218a Purified [H44]](/web/image/product.product/79628/image_1024/%5BAFG-EXB-0658%5D%20AffiAB%C2%AE%20Anti-Hu%20CD218a%20Purified%20%5BH44%5D?unique=d31c23b)
Overview
CD218a, an approximately 62 kDa type I transmembrane glycoprotein, is the alpha subunit of IL-18 receptor heterodimer. It is expressed in various immune cells, including lymphocytes, NK cells, and myeloid cells, as well as in heart, lung, liver, gut and another tissues. IL-18 is a proinflammatory cytokine, that promotes both Th1 and Th2 immune responses, induces IFN-gamma production and activates NK cells.
Specificity:
The mouse monoclonal antibody H44 recognizes an extracellular epitope of CD218a, the alpha subunit of IL-18 receptor.
Antigen
CD218a
Clone
H44
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
Human CD218a expressed on a transfected NK0 cell line
Application
WB, IHC (P), FC (QC tested), IP, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide