![AffiAB® Anti-Hu CD166 Purified [3A6]](/web/image/product.product/79600/image_1024/%5BAFG-EXB-0630%5D%20AffiAB%C2%AE%20Anti-Hu%20CD166%20Purified%20%5B3A6%5D?unique=d31c23b)
Overview
CD166 is a type 1 transmembrane glycoprotein, which is anchored to the actin cytoskeleton through its intracellular domain, whereas its extracellular part binds its ligand CD6. CD166 functions as an adhesion molecule expressed during development of many organs, as well as in hematopoiesis (pluripotent stem cells), endothelial and epithelial linings, endometrium, blastocysts, and in the central and peripheral nervous system (on neurons), as well as on activated T cells and activated monocytes. Multiple isoforms of CD166 have been found.
Specificity:
The mouse monoclonal antibody 3A6 recognizes an extracellular epitope of CD166, a type I transmembrane glycoprotein expressed on neurons, activated T cells, activated monocytes, endothelium, epithelium, endometrium, fibroblasts, pluripotent stem cells, and blastocysts.
Antigen
CD166
Clone
3A6
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1 kappa
Immunogen
cultured human thymic epithelial cells
Application
FC (QC tested), IHC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide