![AffiAB® Anti-Hu CD155 Purified [SKII.4]](/web/image/product.product/79597/image_1024/%5BAFG-EXB-0627%5D%20AffiAB%C2%AE%20Anti-Hu%20CD155%20Purified%20%5BSKII.4%5D?unique=d31c23b)
Overview
CD155 is a type I transmembrane glycoprotein of the nectin family, which serves as an adhesion molecule involved in intercellular and cell-extracellular matrix interactions. CD155 (nectin-like 5) heterodimerizes with CD113 (nectin-3) and this complex binds to CD51/CD61 complex (integrin alphaVbeta3), and to vitronectin. CD155 is also thought to regulate CD44 binding to hyaluronan, and serves as a receptor for poliovirus and cytomegalovirus. It is expressed on endothelial cells, epithelia, central nervous system, and monocytes.
Specificity:
The mouse monoclonal antibody SKII.4 recognizes an extracellular epitope of CD155, a transmembrane glycoprotein, known as poliovirus and cytomegalovirus receptor.
Antigen
CD155
Clone
SKII.4
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
human neuroblastoma SK-L cells
Application
WB, FC (QC tested), IP
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide