![AffiAB® Anti-Hu SUSD2 [W5C5]](/web/image/product.product/79584/image_1024/%5BAFG-EXB-0614%5D%20AffiAB%C2%AE%20Anti-Hu%20SUSD2%20%5BW5C5%5D?unique=06fe5f0)
Overview
SUSD2 (sushi domain containing protein 2) is a type I transmembrane protein, that serves as an important marker of bone marrow-derived mesenchymal stem-like cells (bone marrow stromal cells) . These pluripotent cells are important for techniques of autologous cell therapy, and can be collected from e.g. endometrium, or palatine tonsil. SUSD2 seems to be a tumor supresor, and is down-regulated in colon cancer tissues, whereas it is highly expressed e.g. in breast cancer.
Specificity:
The mouse monoclonal antibody W5C5 recognizes an extracellular epitope of SUSD2, a type I transmembrane protein expressed on mesenchymal stem-like cells. This antibody selectively binds to a MSCs in both bone marrow and endometrium or tonsil, and can be used for their identification and isolation.
Antigen
SUSD2
Clone
W5C5
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
WERI-RB-1 retinoblastoma cells
Application
ICC, FC (QC tested)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide