AffiAB® Anti-HLA-ABCE Purified [TP25.99SF]

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CAT# AFG-EXB-0595
Size: 0.1 mg

228.50 228.5 USD 228.50

228.50

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Overview

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Classical human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules, the non-classical by e.g. HLA-E, HLA-G.


Specificity:

The mouse monoclonal antibody TP25.99SF recognizes an extracellular epitope on HLA-ABC and HLA-E molecules, but not HLA-G. It can be used for discrimination between HLA-G and other HLA-class I antigens.

Antigen

HLA-ABCE

Clone

TP25.99SF

Species Reactivity

Human

Negative Species

N/A

Isotype

Mouse IgG1

Immunogen

IFN-gamma-treated human melanoma cells Colo 38

Application

FC (QC tested), WB, IHC (F)

Regulatory status

RUO

Concentration

1 mg/ml

Format

Purified

Storage / Stability

Store at 2-8°C. Do not freeze.

Storage Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide