![AffiAB® Anti-Hu CD101 Purified [BB27]](/web/image/product.product/79540/image_1024/%5BAFG-EXB-0570%5D%20AffiAB%C2%AE%20Anti-Hu%20CD101%20Purified%20%5BBB27%5D?unique=d31c23b)
Overview
CD101 is a type I transmembrane glycoprotein, which forms disulfide-linked homodimers. It is expressed on activated T cells, as well as on granulocytes, monocytes, dendritic cells or mucosal T cells. It plays a major role in the activation of T cells by skin dendritic cells. Function of CD101 has not been fully elucidated, but in mice its knock-out results in liver autoimmune disease induced by Novosphingobium aromaticivorans.
Specificity:
The mouse monoclonal antibody BB27 recognizes an extracellular epitope of CD101, a 140 kDa disulfide-bonded homodimeric protein expressed on activated T cells, and some other cell types, such as granulocytes and cells of the monocyte/macropgage lineage.
Antigen
CD101
Clone
BB27
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Human thymic clone B12
Application
FC (QC tested), IP, WB, IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide