![AffiAB® Anti-AGPS Purified [AGPS-03]](/web/image/product.product/79506/image_1024/%5BAFG-EXB-0536%5D%20AffiAB%C2%AE%20Anti-AGPS%20Purified%20%5BAGPS-03%5D?unique=06fe5f0)
Overview
AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.
Specificity:
The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.
Antigen
AGPS
Clone
AGPS-03
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
recombinant human AGPS (amino acids 158-384)
Application
WB, FC (IC)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide