![AffiAB® Anti-Ms CD197 Purified [4B12]](/web/image/product.product/79503/image_1024/%5BAFG-EXB-0533%5D%20AffiAB%C2%AE%20Anti-Ms%20CD197%20Purified%20%5B4B12%5D?unique=d31c23b)
Overview
CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.
Specificity:
The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.
Antigen
CD197
Clone
4B12
Species Reactivity
Mouse
Negative Species
N/A
Isotype
Rat IgG2a kappa
Immunogen
Murine CD197-transfected RBL-2H3 cells
Application
FC (QC tested), IP
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide