![AffiAB® Anti-Hu CD324 Purified [67A4]](/web/image/product.product/79387/image_1024/%5BAFG-EXB-0417%5D%20AffiAB%C2%AE%20Anti-Hu%20CD324%20Purified%20%5B67A4%5D?unique=d31c23b)
Overview
CD324 / E-cadherin is an epithelial cell surface molecule, which provides calcium-dependent homophilic interactions with E-cadherin of another cell. These intaractions take part in morphogenetic programs controlling the maintenance of the structural and functional integrity of epithelia and affect invasive potential of epithelial neoplasms. CD324 / E-cadherin is implicated in cell growth and differentiation, cell recognition, and sorting during developmental morphogenesis, as well as in aggregation-dependent cell survival. CD324 / E-cadherin-mediated cell adhesion system is highly regulated from inside the cell by a number of intracellular signaling pathways.
Specificity:
The mouse monoclonal antibody 67A4 recognizes an extracellular epitope of CD324 / E-cadherin, an approximately 100 kDa epithelial cell adhesion molecule, whose detection is important for determination of invasive potential of epithelial neoplasms.
Antigen
CD324
Clone
67A4
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
T-47D cells
Application
FC (QC tested), IP, WB, IHC (F), ICC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide