![AffiAB® Anti-AGR2/AGR3 Purified [AGR3.4]](/web/image/product.product/79370/image_1024/%5BAFG-EXB-0400%5D%20AffiAB%C2%AE%20Anti-AGR2-AGR3%20Purified%20%5BAGR3.4%5D?unique=1da554d)
Overview
AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.
Specificity:
The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa) ; secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
Antigen
AGR2/AGR3
Clone
AGR3.4
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Purified human AGR3 protein
Application
WB, IHC (P), ICC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide