Overview
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.
Specificity:
The antibody AGR3.1 recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa) ; a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
Antigen
AGR3
Clone
AGR3.1
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Purified human AGR3 protein
Application
WB, IHC (P), IHC (F), ICC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide