AffiAB® Anti-HLA-B7 Purified [BB7.1]

https://www.affiab.com/web/image/product.template/105223/image_1920?unique=1da554d
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CAT# AFG-EXB-0392
Size: 0.1 mg

197.00 197.0 USD 197.00

197.00

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Overview

HLA-B7 allele of human HLA class I major histocompatibility (MHC) antigen indicates higher risk of breast cancer and cervical cancer. Expression of HLA-B7 together with HLA-B27 is associated with increased susceptibility to spondyloarthropaties. Flow cytometry detection of these two alleles is being used to screen for patients, who suffer from inflammatory disorders affecting the sacroiliac and intervertebral joints, such as ankylosing spondylosis (AS) . The HLA-B7 antigen (11 alleles) is expressed in 22% of healthy Caucasian individuals.


Specificity:

The mouse monoclonal antibody BB7.1 recognizes an extracellular antigen of HLA-B7 antigen. Although highly specific, it can cross-react with HLA-B42 antigen.

Antigen

HLA-B7

Clone

BB7.1

Species Reactivity

Non-human primates, Human

Negative Species

N/A

Isotype

Mouse IgG1

Immunogen

Papain solubilised HLA-A2, B7

Application

FC (QC tested)

Regulatory status

RUO

Concentration

1 mg/ml

Format

Purified

Storage / Stability

Store at 2-8°C. Do not freeze.

Storage Buffer

Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide