![AffiAB® Anti-BRG1 Purified [BRG-01]](/web/image/product.product/79359/image_1024/%5BAFG-EXB-0389%5D%20AffiAB%C2%AE%20Anti-BRG1%20Purified%20%5BBRG-01%5D?unique=1da554d)
Overview
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.
Specificity:
The antibody BRG-01 recognizes an epitope within C-terminal part of human Brg1, a 205 kDa catalytic subunit of SWI2/SNF2-family chromatin-remodeling complexes.
Antigen
BRG1
Clone
BRG-01
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
Bacterially produced GST-fused protein representing 242 C-terminal amino acids of human Brg1.
Application
WB
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide