![AffiAB® Anti-Cytokeratin 10/13 Purified [DE-K13]](/web/image/product.product/79313/image_1024/%5BAFG-EXB-0343%5D%20AffiAB%C2%AE%20Anti-Cytokeratin%2010-13%20Purified%20%5BDE-K13%5D?unique=1da554d)
Overview
Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratins 10 and 13 both belong to type I family (acidic cytokeratins) .
Specificity:
The mouse monoclonal antibody DE-K13 reacts with cytokeratin 10 (56.5 kDa) and cytokeratin 13 (53 kDa) . Cytokeratins are members of intermediate filaments subfamily of intracellular proteins, represented in epithelial tissues. DE-K13 recognizes only cytokeratin 13 on formalin-fixed, paraffin-embedded tissue sections.
Antigen
Cytokeratin 10/13
Clone
DE-K13
Species Reactivity
Cat, Human
Negative Species
N/A
Isotype
Mouse IgG2a
Immunogen
Cytoskeletal preparation extracted from human ectocervical epithelium.
Application
WB, IHC (P), IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide