![AffiAB® Anti-Hu CD41b Purified [HIP2]](/web/image/product.product/79271/image_1024/%5BAFG-EXB-0301%5D%20AffiAB%C2%AE%20Anti-Hu%20CD41b%20Purified%20%5BHIP2%5D?unique=d31c23b)
Overview
CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Specificity:
The antibody HIP2 reacts with an extracellular epitope on beta (b) subunit of CD41 glycoprotein (light chain; 23 kDa) . CD41 is mainly expressed on platelets and megakaryocytes.
Antigen
CD41b
Clone
HIP2
Species Reactivity
Non-human primates, Human
Negative Species
N/A
Isotype
Mouse IgG3
Immunogen
N/A
Application
FC (QC tested), IHC (F)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide