![AffiAB® Anti-TRIM Purified [TRIM-04]](/web/image/product.product/79207/image_1024/%5BAFG-EXB-0237%5D%20AffiAB%C2%AE%20Anti-TRIM%20Purified%20%5BTRIM-04%5D?unique=d31c23b)
Overview
TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
Specificity:
The antibody TRIM-04 recognizes an intracellular epitope of T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells.
Antigen
TRIM
Clone
TRIM-04
Species Reactivity
Human
Negative Species
Mouse
Isotype
Mouse IgG2a
Immunogen
Recombinant intracellular domain (aa 29-186) of human TRIM.
Application
IP, WB, FC (IC)
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide