Overview
Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days.
Specificity:
The antibody MA2 reacts with µ-chain of human IgM, Fab - region localized epitope.
Antigen
IgM
Clone
MA2
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2b
Immunogen
IgM from human serum.
Application
ELISA
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Tris buffered saline (TBS) , pH 8.0, 15 mM sodium azide