![AffiAB® Anti-Hu IgG (Fab) Purified [4A11]](/web/image/product.product/79189/image_1024/%5BAFG-EXB-0219%5D%20AffiAB%C2%AE%20Anti-Hu%20IgG%20%28Fab%29%20Purified%20%5B4A11%5D?unique=d31c23b)
Overview
Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75% of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.
Specificity:
The mouse monoclonal antibody 4A11 reacts with Fab fragment of human IgG. This antibody detects Fab fragments regardless light chain type.
Antigen
IgG (Fab)
Clone
4A11
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2b
Immunogen
Purified human IgG.
Application
FC (QC tested), WB, ELISA
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide