![AffiAB® Anti-betaIII-Tubulin Purified [TU-20]](/web/image/product.product/79152/image_1024/%5BAFG-EXB-0182%5D%20AffiAB%C2%AE%20Anti-betaIII-Tubulin%20Purified%20%5BTU-20%5D?unique=1da554d)
Overview
The betaIII isoform of tubulin is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
Specificity:
The antibody TU-20 recognizes C-terminal peptide sequence ESESQGPK (aa 441-448) of neuron-specific human betaIII-tubulin.
Antigen
betaIII-Tubulin
Clone
TU-20
Species Reactivity
Dog, Mouse, Rat, Pig, Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide.
Application
FC (IC), WB, IHC (P), ICC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide