![AffiAB® Anti-Insulin Purified [IN-05]](/web/image/product.product/79136/image_1024/%5BAFG-EXB-0166%5D%20AffiAB%C2%AE%20Anti-Insulin%20Purified%20%5BIN-05%5D?unique=1da554d)
Overview
Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population.
Specificity:
The antibody IN-05 reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas; it is also present in tumors of B cell origin such as insulinoma.
Antigen
Insulin
Clone
IN-05
Species Reactivity
Pig, Cow, Human
Negative Species
N/A
Isotype
Mouse IgG1
Immunogen
Porcine insulin.
Application
ELISA, RIA, IHC (P), ICC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide