![AffiAB® Anti-GlcB (M. tuberculosis) Purified [PAb (192) ]](/web/image/product.product/79086/image_1024/%5BAFG-EXB-0116%5D%20AffiAB%C2%AE%20Anti-GlcB%20%28M.%20tuberculosis%29%20Purified%20%5BPAb%20%28192%29%20%5D?unique=1da554d)
Overview
The Mycobacterium tuberculosis antigen GlcB (malate synthase) catalyzes synthesis of malate from glyoxylate and acetyl-CoA. This reaction is part of the glyoxylate cycle, which allows the bacterium to derive its carbon requirements from two-carbon compounds by bypassing the two carbocylation steps of the cytric acid cycle. This enzyme is up-regulated in response to phagocytosis and it is a virulence or persistence factor.
Specificity:
The rabbit polyclonal antibody to GlcB reacts with Mycobacterium tuberculosis protein GlcB (malate synthase, Rv1837c) .
Antigen
GlcB (M. tuberculosis)
Clone
PAb (192)
Species Reactivity
Mycobacterium tuberculosis
Negative Species
N/A
Isotype
Rabbit polyclonal
Immunogen
Recombinant GlcB protein (produced in E. coli)
Application
WB, ELISA
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide