![AffiAB® Anti-Cytokeratin 5/8 Purified [C-50]](/web/image/product.product/79007/image_1024/%5BAFG-EXB-0037%5D%20AffiAB%C2%AE%20Anti-Cytokeratin%205-8%20Purified%20%5BC-50%5D?unique=1da554d)
Overview
Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Specificity:
The antibody C-50 reacts with cytokeratin peptides 5 and 8 (58 and 53 kDa) . Cytokeratins are members of intermediate filaments subfamily of intracellular proteins represented in epithelial tissues.
Antigen
Cytokeratin 5/8
Clone
C-50
Species Reactivity
Rat, Hamster, Pig, Sheep, Dog, Cow, Human, Mouse
Negative Species
Xenopus, Chicken
Isotype
Mouse IgG1
Immunogen
Cytoskeleton preparation from HeLa cells.
Application
IHC (P), IP, WB, ICC
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide