![AffiAB® Anti-HLA-A2 Purified Azide Free [BB7.2]](/web/image/product.product/78993/image_1024/%5BAFG-EXB-0021%5D%20AffiAB%C2%AE%20Anti-HLA-A2%20Purified%20Azide%20Free%20%5BBB7.2%5D?unique=1da554d)
Overview
HLA-A2 (44 kDa) is the most frequent HLA-A allele in human ethnic populations. HLA-A, together with HLA-B and HLA-C, represent human HLA class I major histocompatibility (MHC) antigens. These intrinsic membrane glycoproteins are expressed on nucleated cells and noncovalently associate with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence.
Specificity:
The antibody BB7.2 recognizes an extracellular epitope at the C-terminus of alpha-2 helix and a turn on one of the underlying beta strands within the human HLA-A2 histocompatibility antigen.
Antigen
HLA-A2
Clone
BB7.2
Species Reactivity
Human
Negative Species
N/A
Isotype
Mouse IgG2b
Immunogen
HLA-A2 solubilised by papain
Application
FC (QC tested), IP
Regulatory status
RUO
Concentration
1 mg/ml
Format
Purified Azide Free
Storage / Stability
Store at 2-8°C. Do not freeze.
Storage Buffer
Phosphate buffered saline (PBS), pH 7.4