Available Sizes: 50 μg, 100 μg.
Background
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7 and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on Antigen presenting cells (such as dendritic cells, macrophages and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Host
Armenian Hamster.
Species Reactivity
Mouse.
Synonyms
T-lymphocyte activation Antigen CD80, Cd80, Activation B7-1 Antigen, B7.
Conjugation
Unconjugated.
Isotype
Armenian Hamster IgG.
Applications
FCM.
Concentration
0.5 mg/mL.
Buffer
PBS with 0. 05% Proclin300.
Storage Conditions
Store at 2~8°C. Do not freeze.
Gene-ID
12519.