Available Sizes: 25μg, 100 μg.
Background
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102) and ICAM-3 (CD50).
Host
Mouse.
Species Reactivity
Human.
Synonyms
Integrin alpha-L, LFA-1A, CD11A, ITGAL.
Conjugation
Unconjugated.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
0.5 mg/mL.
Buffer
PBS with 0. 05% Proclin300.
Storage Conditions
Store at 2~8°C. Do not freeze.
Gene-ID
3683.