Available Sizes: 25μg, 50 μg, 100 μg, 200 μg.
Background
CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2 and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an Antigen co-receptor on T cells that interacts with MHC class I on Antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).
Host
Mouse.
Species Reactivity
Rat.
Synonyms
T-cell surface glycoprotein CD8 alpha chain, CD8A, T-lymphocyte differentiation Antigen T8/Leu-2, MAL.
Conjugation
PerCP/Cyanine5.5.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
0.2 mg/mL.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
24930.