Available Sizes: 25μg, 50 μg, 100 μg, 200 μg.
Background
CD45 is a 180-220 kD protein also known as leukocyte common Antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state and cell maturation. CD45 functions in signal transduction through T and B cell Antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3 and CD4. The OX-1 Antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.
Host
Mouse.
Species Reactivity
Rat.
Synonyms
Receptor-type tyrosine-protein phosphatase C, Leukocyte common Antigen, LCA, T200, Ly-5, Ptprc.
Conjugation
PerCP/Cyanine5.5.
Isotype
Mouse IgG1, κ.
Applications
FCM.
Concentration
0.2 mg/mL.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
19265.