Available Sizes: 20 Tests, 50 Tests, 100 Tests, 500 Tests.
Background
CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 Antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 Antibody has been mapped to a region on both the standard, CD44s and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 Antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.
Host
Mouse.
Species Reactivity
Rat.
Synonyms
Pgp-1, H-CAM, CD44s, CD44H.
Conjugation
PerCP/Cyanine5.5.
Isotype
Mouse IgG2a, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
12505.