Available Sizes: 20 Tests, 50 Tests, 100 Tests, 500 Tests.
Background
Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI) -linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6. 2 haplotype (e. g., AKR, C57BL, C57BR, DBA/2, SJL, SWR and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6. 1 haplotype (e. g., BALB/c, CBA, C3H/He, DBA/1 and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6. 1 and Ly6. 2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
Host
Rat.
Species Reactivity
Mouse.
Synonyms
Ly6a, Ly6, Ly-6A.2/Ly-6E.1, SCA-1, TAP.
Conjugation
PerCP/Cyanine5.5.
Isotype
Rat IgG2a, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Gene-ID
110454.