Available Sizes: 50 Tests, 100 Tests, 200 Tests, 500 Tests.
Background
CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1. 7. 4 Antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion and function in Antigen presentation to T cells and leukocyte migration to inflammatory tissues.
Host
Rat.
Species Reactivity
Mouse.
Synonyms
Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54, Icam-1.
Conjugation
PerCP/Cyanine5.5.
Isotype
Rat IgG2b, κ.
Applications
FCM.
Concentration
N/A.
Buffer
PBS with 0. 05% Proclin300, 1% BSA.
Storage Conditions
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Gene-ID
15894.